Oxford Healthspan was founded by Leslie Kenny, an Oxford-based, Harvard-educated longevity expert who turned a devastating autoimmune diagnosis into a mission to help others age better. Now 60 with a biological age of just 21, Leslie is living proof of what cellular renewal can look like in practice. Her company’s Primeadine line — including the Original and GF formulations — is built on that same philosophy: that aging doesn’t have to mean decline, but can instead mean optimization, balance, and renewed vitality at every stage of life.

Primeadine Original is Oxford Healthspan’s flagship food-derived spermidine supplement, sourced from the longevity islands of Japan. It’s made from concentrated, defatted Japanese wheat germ, providing a unique polyamine matrix that includes other beneficial, naturally occurring polyamines, spermine and putrescine, in a format your body can utilize.  This unique combination supports autophagy (the body’s process of cellular renewal) to promote smoother skin, stronger hair and nails, and a more balanced sense of energy, focus, and well-being.